Recent Publications

1. Martel, R., Botros, I., Rounseville, M., et al, (2002). Multiplexed screening assay for mRNA combining nuclease protection with luminescent array detection. Assay and Drug Development Technologies, 1 (1-1):61-71.

2. Martel, R., Rounseville, M., Botros, I., et al, (2002). Multiplexed Chemiluminescence Assays in ArrayPlates for High-Throughput Measurement of Gene Expression, Progress in Bimedical Optics and Imaging, 3:35-43.

3. Martel. R., Rounseville, M., Botros, I., et al, (2002). “Multiplexed Molecular Profiling (MMP) Transcription Assay in ArayPlates for High-Throughput Measurement of Gene Expression.” Gene Cloning and Expression Technologies, Q. Lu and M. Weiner, Eds., Eaton Publishing, Natick.

4. Seligmann, B., (2003). “Mining the Transcriptome Using High-Throughput Multiplexed mRNA Profiling.” PharmacoGenomics, 3:36-43.

5. Martel, R., Staples, R., Hinton, J., et al, (2003). “Array Formats” in “Microarray Technologies and Applications”, Microarray Technologies and Applications, Springer-Verlag, Heidelberg.

6. Sawada, H., Taniguchi, K., Takami, K., et al, (2006). “Improved toxicogenomic screening for drug-induced phospholipidosis using a multiplexed quantitative gene expression ArrayPlate assay”. Toxicology in Vitro, 20:1506-1513.

7. Bakir, F., Kher, S., Pannala, M., et al, (2007). “Discovery and structure–activity relationship studies of indole derivatives as liver X receptor (LXR) agonists” Biorg and Med Chem Letters, 17: 3473-3479.

8. Kris, R., Felder, S., Deyholos, M., et al, (2007). “High-Throughput, High-Sensitivity Analysis of Gene Expression in Arabidopsis” Plant Physiol. 144: 1256-1266.

9. Roberts, R., Sabalos, C., Martel, R., et al, ( 2007). “Quantitative Nuclease Protection Assay in Paraffin-Embedded Tissue Replicates Prognostic Microarray Gene Expression in Diffuse Large-B-Cell Lymphoma” Laboratory Investigation, 87: 979-997.

10. Rimsza, L., LeBlanc, M., Unger, J., et al., (2008). “Gene expression predicts overall survival in paraffin embedded tissues of diffuse large B cell lymphoma treated with R-CHOP” Blood, Online June 10, 2008 doi: 10.1182/blood-2008-02-137372.

11. Altar CA, Hunt RA, Jurata LW, Webster MJ, Derby E, Gallagher P, Lemire A, Brockman J, Laeng P (2008). “Insulin, IGF-1, and muscarinic agonists modulate schizophrenia-associated genes in human neuroblastoma cells.” Biological Psychiatry, 64:1077-1087.

12. Fichorova, R. N., Trifonova, R. T., Doncel, G. F., (2009) “Polyanionic Microbicides Modify
Toll-Like Receptor-Mediated Cervicovaginal Immune Responses.” Antimicrobial Agents and
Chemotherapy, April 2009: 1490-1500.

13. Altar CA, Vawter MP, Ginsberg SD (2009). “Target identification for CNS diseases by transcriptional profiling.” Neuropsychopharmacology, 34:18-54.

14. Pechold S, Stouffer M, et. al., (2009) “Transcriptional analysis of intracytoplasmically stained, FACS-purified cells by high throughput, quantitative nuclease protection.” Nature Biotechnology, 27, 1038-1042.

ArrayPlate Pilot Studies

ArrayPlate Pilot Studies 

HTG realizes that choosing a new high throughput gene expression platform is a complicated and expensive investment process. To aid in your decision making process, we are happy to provide cost-effective pilot studies which yield real data in your experimental system.

Included in the pilot study are:

– The design of an up to 45 gene qCustom™ ArrayPlate Assay.
– The use of our in house service to run a small proof of concept study of up to five 96 well plates.
– Basic data analysis services for your results.

Contact us at support@htgenomics.com for more details.

Custom Pilot Studies

Interested in qNPA technology, but our standard pilot study doesn’t fit your research needs? Please contact your local sales representative and we’ll work with you to design the pilot study that will show you how effective the qNPA ArrayPlate approach is.

We also offer instrument demos and trials sizes of our qFix™ ArrayPlates for use in your own lab. Contact us for more details.

Brochures

Academic Research -
High Throughput Gene Expression Analysis

Drug Discovery -
Multiplexed Biomarker-Driven Drug Discovery

Press Releases

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