Recent Publications
Martel, R.R., I.W. Botros, M.P. Rounseville, J.P. Hinton, R.R. Staples, D.A. Morales, J.B. Farmer, and B.E. Seligmann. Multiplexed screening assay for mRNA combining nuclease protection with luminescent array detection. Assay and Drug Development Technologies. 2002, 1 (1-1):61-71.
Martel, R.R., M.P. Rounseville, I.W. Botros, and B.E. Seligmann. Multiplexed Chemiluminescence Assays in ArrayPlates for High-Throughput Measurement of Gene Expression, Progress in Biomedical Optics and Imaging, 2002, 3:35-43.
Martel. R., M.P. Rounseville, I.W. Botros, R. Kris, S. Felder and B.E. Seligmann. Multiplexed Molecular Profiling (MMP) Transcription Assay in ArrayPlates for High-Throughput Measurement of Gene Expression in Gene Cloning and Expression Technologies, Q. Lu and M. Weiner, Eds., Eaton Publishing, Natick (2002).
Seligmann, B. Mining the Transcriptome Using High-Throughput Multiplexed mRNA Profiling PharmacoGenomics, 2003, 3:36-43
Martel, R.R., R.R. Staples, J.P. Hinton, I.W. Botros, M.P. Rounseville, and B.E. Seligmann, “Array Formats” in “Microarray Technologies and Applications”, U.R. Muller and D. Nicolau, Eds, Springer-Verlag, Heidelberg.
Sawada, H., Taniguchi, K., Takami, K. (2006) “Improved toxicogenomic screening for drug-induced phospholipidosis using a multiplexed quantitative gene expression ArrayPlate assay”. Toxicology in Vitro, 20:1506-1513.
Farid Bakir, Sunil Kher, Madhavi Pannala, Norma Wilson, Trang Nguyen, Ila Sircar, Kei Takedomi, Chiaki Fukushima, James Zapf, Kui Xu, et al (2007) “Discovery and structure–activity relationship studies of indole derivatives as liver X receptor (LXR) agonists” Bioorg. & Med. Chem Lett, 17: 3473-3479
Richard Martin Kris, Stephen Felder, Michael Deyholos, Georgina M. Lambert, James Hinton, Ihab Botros, Ralph Martel, Bruce Seligmann, and David W. Galbraith (2007) “High-Throughput, High-Sensitivity Analysis of Gene Expression in Arabidopsis” Plant Physiol. 144: 1256-1266
Robin Roberts, Costi Sabalos, Ralph Martel, Michael LeBlanc, Joseph Unger, Ihab Botros, Bruce Seligmann, Thomas Miller, Thomas Grogan and Lisa Rimsza (2007) “Quantitative Nuclease Protection Assay in Paraffin-Embedded Tissue Replicates Prognostic Microarray Gene Expression in Diffuse Large-B-Cell Lymphoma” Laboratory Investigation, 87: 979-997.
Lisa Rimsza, Michael LeBlanc, Joseph Unger, Thomas Miller, Thomas Grogan, Daniel Persky, Ralph Martel, Constantine Sabalos, Bruce Seligmann, Rita Braziel, Elias Campo, Andreas Rosenwald, Joseph Connors, Laurie Sehn, Nathalie Johnson, and Randy Gascoyne (2008) “Gene expression predicts overall survival in paraffin embedded tissues of diffuse large B cell lymphoma treated with R-CHOP” Blood, Published online June 10, 2008 doi:10.1182/blood-2008-02-137372.

